Somatostatin analogue scintigraphy in Merkel cell tumours.
Identifieur interne : 003207 ( Main/Exploration ); précédent : 003206; suivant : 003208Somatostatin analogue scintigraphy in Merkel cell tumours.
Auteurs : RBID : pubmed:12828740English descriptors
- KwdEn :
- Aged, Carcinoma, Merkel Cell (radionuclide imaging), Female, Humans, Immunohistochemistry, Liver Neoplasms (radionuclide imaging), Liver Neoplasms (secondary), Lymphatic Metastasis (radionuclide imaging), Male, Pancreatic Neoplasms (radionuclide imaging), Pancreatic Neoplasms (secondary), Radiopharmaceuticals (diagnostic use), Somatostatin (analogs & derivatives), Somatostatin (diagnostic use).
- MESH :
- chemical , analogs & derivatives : Somatostatin.
- chemical , diagnostic use : Radiopharmaceuticals, Somatostatin.
- radionuclide imaging : Carcinoma, Merkel Cell, Liver Neoplasms, Lymphatic Metastasis, Pancreatic Neoplasms.
- secondary : Liver Neoplasms, Pancreatic Neoplasms.
- Aged, Female, Humans, Immunohistochemistry, Male.
Abstract
Merkel cell tumours are rare neoplasms of the skin with frequent regional and distant metastases. Scintigraphy with the radiolabelled somatostatin analogue octreotide is a possible method for in vivo localization of the primary tumour and its metastases.
PubMed: 12828740
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<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Somatostatin analogue scintigraphy in Merkel cell tumours.</title><author><name sortKey="Durani, B K" uniqKey="Durani B">B K Durani</name><affiliation wicri:level="3"><nlm:affiliation>Department of Dermatology, University of Heidelberg, Voss-Str.2, 69115 Heidelberg, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Dermatology, University of Heidelberg, Voss-Str.2, 69115 Heidelberg</wicri:regionArea><placeName><region type="land" nuts="1">Bade-Wurtemberg</region><region type="district" nuts="2">District de Karlsruhe</region><settlement type="city">Heidelberg</settlement></placeName></affiliation></author><author><name sortKey="Klein, A" uniqKey="Klein A">A Klein</name></author><author><name sortKey="Henze, M" uniqKey="Henze M">M Henze</name></author><author><name sortKey="Haberkorn, U" uniqKey="Haberkorn U">U Haberkorn</name></author><author><name sortKey="Hartschuh, W" uniqKey="Hartschuh W">W Hartschuh</name></author></titleStmt><publicationStmt><date when="2003">2003</date><idno type="RBID">pubmed:12828740</idno><idno type="pmid">12828740</idno><idno type="wicri:Area/Main/Corpus">003462</idno><idno type="wicri:Area/Main/Curation">003462</idno><idno type="wicri:Area/Main/Exploration">003207</idno></publicationStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Aged</term><term>Carcinoma, Merkel Cell (radionuclide imaging)</term><term>Female</term><term>Humans</term><term>Immunohistochemistry</term><term>Liver Neoplasms (radionuclide imaging)</term><term>Liver Neoplasms (secondary)</term><term>Lymphatic Metastasis (radionuclide imaging)</term><term>Male</term><term>Pancreatic Neoplasms (radionuclide imaging)</term><term>Pancreatic Neoplasms (secondary)</term><term>Radiopharmaceuticals (diagnostic use)</term><term>Somatostatin (analogs & derivatives)</term><term>Somatostatin (diagnostic use)</term></keywords><keywords scheme="MESH" type="chemical" qualifier="analogs & derivatives" xml:lang="en"><term>Somatostatin</term></keywords><keywords scheme="MESH" type="chemical" qualifier="diagnostic use" xml:lang="en"><term>Radiopharmaceuticals</term><term>Somatostatin</term></keywords><keywords scheme="MESH" qualifier="radionuclide imaging" xml:lang="en"><term>Carcinoma, Merkel Cell</term><term>Liver Neoplasms</term><term>Lymphatic Metastasis</term><term>Pancreatic Neoplasms</term></keywords><keywords scheme="MESH" qualifier="secondary" xml:lang="en"><term>Liver Neoplasms</term><term>Pancreatic Neoplasms</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Aged</term><term>Female</term><term>Humans</term><term>Immunohistochemistry</term><term>Male</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Merkel cell tumours are rare neoplasms of the skin with frequent regional and distant metastases. Scintigraphy with the radiolabelled somatostatin analogue octreotide is a possible method for in vivo localization of the primary tumour and its metastases.</div></front></TEI><pubmed><MedlineCitation Owner="NLM" Status="MEDLINE"><PMID Version="1">12828740</PMID><DateCreated><Year>2003</Year><Month>06</Month><Day>27</Day></DateCreated><DateCompleted><Year>2003</Year><Month>09</Month><Day>16</Day></DateCompleted><DateRevised><Year>2004</Year><Month>11</Month><Day>17</Day></DateRevised><Article PubModel="Print"><Journal><ISSN IssnType="Print">0007-0963</ISSN><JournalIssue CitedMedium="Print"><Volume>148</Volume><Issue>6</Issue><PubDate><Year>2003</Year><Month>Jun</Month></PubDate></JournalIssue><Title>The British journal of dermatology</Title><ISOAbbreviation>Br. J. Dermatol.</ISOAbbreviation></Journal><ArticleTitle>Somatostatin analogue scintigraphy in Merkel cell tumours.</ArticleTitle><Pagination><MedlinePgn>1135-40</MedlinePgn></Pagination><Abstract><AbstractText Label="BACKGROUND" NlmCategory="BACKGROUND">Merkel cell tumours are rare neoplasms of the skin with frequent regional and distant metastases. Scintigraphy with the radiolabelled somatostatin analogue octreotide is a possible method for in vivo localization of the primary tumour and its metastases.</AbstractText><AbstractText Label="OBJECTIVES" NlmCategory="OBJECTIVE">To estimate the diagnostic value of indium (111) -octreotide scintigraphy (Octreoscan in detecting metastases.</AbstractText><AbstractText Label="METHODS" NlmCategory="METHODS">Scans of 11 patients with Merkel cell carcinoma were evaluated, in whom scintigraphy was performed in addition to the conventional investigations, chest X-ray, ultrasonography and computed tomography (CT).</AbstractText><AbstractText Label="RESULTS" NlmCategory="RESULTS">In four cases metastases were found both by scintigraphy and by conventional methods; two investigations showed a suspicious accumulation of radioactivity on scintigraphy that could not be confirmed by CT and clinical progression. In three cases CT-verified metastases were not found by scintigraphy. Two patients were found to be tumour free, i.e. free of metastases by scintigraphy and conventional methods, indicating true-negative results.</AbstractText><AbstractText Label="CONCLUSION" NlmCategory="CONCLUSIONS">These data confirm that scintigraphy with the radiolabelled somatostatin analogue octreotide is not clinically helpful in detecting metastases from Merkel cell carcinoma. In this relatively small sample the method generated false-positive or false-negative results in five of 11 cases.</AbstractText></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Durani</LastName><ForeName>B K</ForeName><Initials>BK</Initials><Affiliation>Department of Dermatology, University of Heidelberg, Voss-Str.2, 69115 Heidelberg, Germany.</Affiliation></Author><Author ValidYN="Y"><LastName>Klein</LastName><ForeName>A</ForeName><Initials>A</Initials></Author><Author ValidYN="Y"><LastName>Henze</LastName><ForeName>M</ForeName><Initials>M</Initials></Author><Author ValidYN="Y"><LastName>Haberkorn</LastName><ForeName>U</ForeName><Initials>U</Initials></Author><Author ValidYN="Y"><LastName>Hartschuh</LastName><ForeName>W</ForeName><Initials>W</Initials></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType>Journal Article</PublicationType></PublicationTypeList></Article><MedlineJournalInfo><Country>England</Country><MedlineTA>Br J Dermatol</MedlineTA><NlmUniqueID>0004041</NlmUniqueID><ISSNLinking>0007-0963</ISSNLinking></MedlineJournalInfo><ChemicalList><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance>Radiopharmaceuticals</NameOfSubstance></Chemical><Chemical><RegistryNumber>138661-02-6</RegistryNumber><NameOfSubstance>pentetreotide</NameOfSubstance></Chemical><Chemical><RegistryNumber>51110-01-1</RegistryNumber><NameOfSubstance>Somatostatin</NameOfSubstance></Chemical></ChemicalList><CitationSubset>IM</CitationSubset><MeshHeadingList><MeshHeading><DescriptorName MajorTopicYN="N">Aged</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N">Carcinoma, Merkel Cell</DescriptorName><QualifierName MajorTopicYN="Y">radionuclide imaging</QualifierName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N">Female</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N">Humans</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N">Immunohistochemistry</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N">Liver Neoplasms</DescriptorName><QualifierName MajorTopicYN="N">radionuclide imaging</QualifierName><QualifierName MajorTopicYN="N">secondary</QualifierName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N">Lymphatic Metastasis</DescriptorName><QualifierName MajorTopicYN="N">radionuclide imaging</QualifierName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N">Male</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N">Pancreatic Neoplasms</DescriptorName><QualifierName MajorTopicYN="N">radionuclide imaging</QualifierName><QualifierName MajorTopicYN="N">secondary</QualifierName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N">Radiopharmaceuticals</DescriptorName><QualifierName MajorTopicYN="Y">diagnostic use</QualifierName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N">Somatostatin</DescriptorName><QualifierName MajorTopicYN="Y">analogs & derivatives</QualifierName><QualifierName MajorTopicYN="Y">diagnostic use</QualifierName></MeshHeading></MeshHeadingList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="pubmed"><Year>2003</Year><Month>6</Month><Day>28</Day><Hour>5</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2003</Year><Month>9</Month><Day>17</Day><Hour>5</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>2003</Year><Month>6</Month><Day>28</Day><Hour>5</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">12828740</ArticleId><ArticleId IdType="pii">5338</ArticleId></ArticleIdList></PubmedData></pubmed></record>Pour manipuler ce document sous Unix (Dilib)
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